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Neurovascular Dysfunction in Brain Diseases: Mechanisms and Therapeutic Strategies – Insights from Ischemic Stroke and Alzheimer’s Disease


RWD Speckle Webinar

This webinar will explore two research perspectives:
– Oxidative Stress-Induced Astrocytic Collagen Biosynthesis and Neuronal Death in Ischemic Stroke
– Rescue of Early Alzheimer’s Disease Neurovascular Coupling Deficits by Enhancing Cerebrovascular Smooth Muscle Calcium Oscillations

 

📅 Date: August 27, 2026
⏰ Time: 7:00 PM KST / 7:00 PM JST / 6:00 PM Beijing Time / 10:00 AM UTC
🌐 Language: English
For this webinar, we are pleased to welcome Prof. C. Justin Lee, Director of the Center for Memory and Glioscience at the Institute for Basic Science (IBS), Republic of Korea, as the Special Guest. Dr. Jae-Hun Lee from IBS and Dr. Xing-Hua Quan from Westlake University will share their latest research insights, exploring the mechanisms and emerging intervention strategies underlying neurovascular dysfunction in brain diseases.
📚 What you’ll learn:
– Validating the role of reactive oxygen species in ischemic stroke using mouse and nonhuman primate photothrombotic models
– Uncovering oxidative stress-induced astrocyte activation and fibprotic scar formation
– Identifying the H2O2-FUT8-COL1 axis as a potential therapeutic target
– Demonstrating neurovascular coupling dysfunction as an early pathological feature of Alzheimer’s disease
– Elucidating the role of cerebrovascular smooth muscle calcium oscillations in neurovascular coupling
– Unveiling a novel, active regulatory role of neurovascular coupling
👨‍⚕️ Speaker 1:
Dr. Jae-Hun Lee, Senior Researcher, Center for Memory and Glioscience, Institute for Basic Science (IBS), Republic of Korea
👨‍⚕️ Speaker 2:
Speaker of RWD Speckle Webinar
Dr. Xing-Hua Quan, Doctoral Researcher, Westlake University, China
Free Webinar

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