R821侧面图
R821 Fiber photometry system 1
R821侧面图
R821 Fiber photometry system 1

R821 Tricolor Multichannel Fiber Photometry System

R821 tricolor multichannel fiber photometry system is compatible with optoelectronics equipment. It has different wavelengths of excited light, 410nm, 470nm or 560nm, of which 410 is used to acquire reference signal and eliminate noise. The system can record signal of green fluorescence indicator like GCaMP and dLight or neurotransmitter probe and red fluorescence indicator like RCaMP, jrGECO1a or neurotransmitter probe.

And also it can be applied to record the neural signal for 9 sites at the same time.

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Overview

The fiber photometry system records changes in the fluorescence intensity of neurons in a specific brain area to reflect neuronal population activity. In the study of neural circuits, the fiber photometry system can perform long-term stable monitoring of the neurons of freely moving animals, and explore the correlation between neural activity and animal behavior.

Main Applications:

  • Ca2 + and neurotransmitter signal detection
  • Study the function of neural circuits
  • Explore the mechanisms of neurological diseases
  • Develop new fluorescent sensor probe
  • Experiment of optical principle

Features

  • Three kinds of excitation light sources, that is 410nm、470nm and 560nm, are respectively used for excitation
    of reference, green fluorescence and red fluorescence;
    Support up to 9 channels, suitable for simultaneous experiment of multiple animals or multiple brain
    locations;
  • Dual highly sensitive detectors enabling independent and sequential detection to avoid interference of
    fluorescence excitation and detection, acquiring more accurate signal;
    Professional acquisition and analysis softwares are flexible and easy to operate with data processing functions
    available. No matlab programming is required;
  • Supports multiple acquisition modes including continuous acquisition, interval acquisition, acquisition upon
    trigger, delayed acquisition and timing acquisition;
  • Live display of DeltaF/F acquisition to check scale of signal changes during acquisition;
  • Customized adjustment of output signal parameter, easily trigger and control external excitation equipment
    to achieve closed-cycle control of excitation and recording;
  • Compatible with optogenetics for recording and stimulation at the same site.

 

Specifications

Wavelength of excitation light R821 : 410nm  470nm   560nmR810 : 410nm  470nm
Power Min 0µW, Max≥100µW, adjustable with an accuracy of 0.1µW
Number of channels 9
Frame rate of fluorescent sampling Max 250fps
Digital signal interface 4Input 4Output
Signal output Output frequency 0-500Hz, adjustable output pulse width and duration
Marking Manual marking (10), automatic marking (4), ROI marking (9)
Behavior camera 1920*1080(30fps) 1280*720(60fps) Switchable among multiple frame rates of resolution
Compatible Compatible with optogenetics for recording and stimulation at the same site.

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