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RWD Inhalation Anesthesia Machines-An Overview and Recommendation

   |  January 16, 2023

Generally, there are some risks and side effects in animal intravenous anesthetics surgery.

Large damage to animal health
● Discomfort is easy to occur when the injection is given.
● It can possibly cause severe respiratory and cardiovascular depression during induction of anesthesia.

Low efficiency
● Complicated procedures in pre-intravenous anesthetics.
● Not easy to control the administration.
● Depth and level of anaesthesia can not be effectively controlled.
● Unable to anesthetize multiple animals simultaneously.

Unsafety
● High risk to animal death
● Personnel easily bitten or scratched by laboratory animals

Limited applications
● Only used for a small range of animal surgeries, such as with myasthenia gravis.
● Unable to accurately reflect the signs of animal metabolism, such as with drug toxicity evaluation research.

Inhalation gas anesthetics can be used safely and effectively for general animal anesthesia surgeries. In this article, we introduce the main benefits of inhalation anesthesia, and overview of RWD animal inhalation anesthesia machines.

Inhalation Gas Anesthesia Benefits

Animal Welfare
● Inhalation anesthesia hardly interferes with an animal’s liver and kidney metabolism.
● Non-invasive operation and low complication risk after recovery, thus ensuring the welfare of laboratory animals.

Animal Safety
● The output concentration and depth of anesthesia can be precisely controlled.
● Oxygen is supplied along with anesthesia, ensuring oxygenation to the body, and reducing risks involved with anesthesia.
● Helps protect internal organs.
● Can easily be used to suppress stress response.

Personnel Safety
● Non-invasive anesthetic wasted gases with the help of gas evacuation apparatus and closed-circle connection design.
● No need to get in touch with injection needle and avoid the bitten and scratched by animal.
● Easy operation and set up, also could support multiple channel experiment with different experiment requirement.

Convenient
● Real-time adjustment of anesthesia status, stable and rapid recovery from anesthesia, easy to operation.
● Multiple animals can be anesthetized simultaneously, simply, and efficiently.

Wide Range of Application
● Used for rats, mice, hamsters, guinea pigs, rabbits, cats, dogs, and other animals weighing less than 100 kg (220 lb).
● Prolonged anesthesia: such as in open thoracotomy, imaging observation surgery, etc.
● Abbreviated anesthesia: such as with orbital blood collection from rats, marking animals, simple animal trauma treatment, etc.
● Overdosing of anesthesia: such as with animal euthanasia, in-depth study of anesthesia, etc.

Easy to Use
● Simple to operate and easy to learn how to use.
● Easy to set up and disassemble.

RWD Small Animal Anesthesia Machines

R500 Compact Small Animal anesthesia machine

Key message: A Standard and Easy Choice
Features:

● Small size, saving laboratory space.
● Ability to attach different components to meet diversified experimental needs; such as extended flow meter components (Different gas sources such as laughing gas, carbon dioxide, nitrogen, etc. can be attached).

R540 enhanced small animal anesthesia machine

Key message: A Classic Choice and Best-seller for the Past Ten Years
Features:
● Wall-mount design, can be easily installed and hung on the wall to make full use of laboratory space.
● Stainless steel handle, convenient to be picked up and taken on the go, moved around, or used at any time.

R550 Multi-output animal anesthesia machine

Key message: first choice for high-throughput anesthesia
Features:

● The unique design of the induction box and anesthesia mask can simultaneously induce and maintain anesthesia, saving experimental time and improving work efficiency.
● The air channel for each anesthesia mask is able to be controlled independently, allowing five small animals to receive a proper amount of anesthesia simultaneously, or to give anesthesia only to select animals that need it.

R520/R530 Moveable small animal anesthesia machine

Key message: the preferred choice for mobility
Features:

● Provides integrate gas supply, induction of anesthesia, recovery of waste anesthetic gases, is convenient to set up and take down, and saves space.
● Swivel casters with locks provide easy stop and go, making mobile operation and unified management convenient.

Recommended Solutions for Animal Surgery and Modeling Applications

Multi-function animal anesthesia solutions

● It can meet the anesthetic needs of 1-5 animals at the same time, and is compatible with MRI, PET, and SPECT imaging systems.
● The tube and mask can be placed and fixed arbitrarily on the desktop, and the height of the mask can be adjusted up and down.
● Provides active waste gas recovery to better protect the physical and mental health of operating personnel.

Stereotaxic animal anesthesia solutions

● Different types of locators and adapters can be exchanged to meet the needs of different stereotaxic brain surgeries.
● Provides active waste gas recovery to better protect the physical and mental health of operating personnel.

Combination of Ventilation to Anesthesia System for Small Animal
● Surgery for animals that cannot breathe on their own due to long-term application or certain diseases that cause respiratory dysfunction.
● Suitable for mice, rats, guinea pigs and other animals weighing less than 1 kg (2.2 lb).

Combination of Ventilation to Anesthesia System for Large Animal
● Suitable for use on pigs, monkeys, dogs, cats, and other large animals weighing around 100 kg (220 lb), this is a complete set of solutions for respiratory monitoring under anesthesia, bringing more security to large animals undergoing experimentation.

Some References

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[4] Battery-Free and Wireless Smart Wound Dressing for Wound Infection Monitoring and Electrically Controlled On-Demand Drug Delivery.Gang Xu,Yanli Lu,Chen Cheng,et al.Advance Punctional Materials, 2021,31(26).
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[11] Cocaine-induced structural and functional impairments of the glymphatic pathway in mice.W Chen, P Huang, H Zeng, J Lin, Z Shi… – Brain, Behavior, and …, 2020 – Elsevier.
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