Aiming to micromanipulators, you only hold glass microelectrodes in patch clamp experiments comes to mind? Now the MM-500 Motorized Micromanipulator offers much more than that. It can be used in combination with different syringe pumps to achieve nanoscale or microscale quantitative and fixed-speed injection or suction.
Applications of micromanipulation in patch-clamp, microinjection, and precision mechanics will be introduced in detail below.
Patch Clamp Experiment What we can offer: By moving the glass microelectrode clamped on the amplifier probe, by selecting different recording modes (cell-attached, whole-cell mode, etc.), the microelectrode is tightly sealed with the cell membrane, and the signal on the cell membrane is recorded. The scenarios are: a. Ion channel-related diseases research; b. Research on ion channel function; c. Active drug screening studies; d. Research on the mechanism of the drug; e. Other related research
Microinjection experiment 2.1 MM-500 Motorized Micromanipulator & R480 Nanoliter Injection Pump What we can offer: Nanoscale quantitative and constant-speed injection or suction is performed by moving the glass microelectrode clamped on the R480 nanoliter injection pump. The scenarios are: a. RNA microinjection of Xenopus oocytes; b. Microinjection of zebrafish embryos; c. Insect and protozoan egg cells, larvae, etc. injection (Drosophila, C. Elegans); d. Microinjection of mammalian cells; e. Other related research
2.2 MM-500 Motorized Micromanipulator & KDS Legato 130 Microsyringe Pump What we can offer: Micro-liter quantitative and constant-speed injection or suction is performed by moving the injection needle clamped on the KDS micro-injection pump. The scenarios are: a. Microinjection administration; b. Intracranial virus or tracer injection; c. Eyeball injection; d. Other related research
Precision machinery What we can offer: By moving the gripper, pressure tests can be performed on different materials, etc. The scenarios are: a. Microscale elastic modulus test of hydrogel(eg. AFM probe); b. Performance test of biomimetic material in the mouth area of Nepenthes; c. Other related research
To learn more about micromanipulators, click here.