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MM-500 Motorized Micromanipulator— Multiple Experimental Scenarios Application

   |  April 14, 2022

Aiming to micromanipulators, you only hold glass microelectrodes in patch clamp experiments comes to mind?
Now the MM-500 Motorized Micromanipulator offers much more than that. It can be used in combination with different syringe pumps to achieve nanoscale or microscale quantitative and fixed-speed injection or suction.

Applications of micromanipulation in patch-clamp, microinjection, and precision mechanics will be introduced in detail below.

  1. Patch Clamp Experiment
    What we can offer: By moving the glass microelectrode clamped on the amplifier probe, by selecting different recording modes (cell-attached, whole-cell mode, etc.), the microelectrode is tightly sealed with the cell membrane, and the signal on the cell membrane is recorded.
    The scenarios are:
    a. Ion channel-related diseases research;
    b. Research on ion channel function;
    c. Active drug screening studies;
    d. Research on the mechanism of the drug;
    e. Other related research
  2. Microinjection experiment
    2.1 MM-500 Motorized Micromanipulator & R480 Nanoliter Injection Pump
    What we can offer: Nanoscale quantitative and constant-speed injection or suction is performed by moving the glass microelectrode clamped on the R480 nanoliter injection pump.
    The scenarios are:
    a. RNA microinjection of Xenopus oocytes;
    b. Microinjection of zebrafish embryos;
    c. Insect and protozoan egg cells, larvae, etc. injection (Drosophila, C. Elegans);
    d. Microinjection of mammalian cells;
    e. Other related research

2.2 MM-500 Motorized Micromanipulator & KDS Legato 130 Microsyringe Pump
What we can offer: Micro-liter quantitative and constant-speed injection or suction is performed by moving the injection needle clamped on the KDS micro-injection pump.
The scenarios are:
a. Microinjection administration;
b. Intracranial virus or tracer injection;
c. Eyeball injection;
d. Other related research

  1. Precision machinery
    What we can offer: By moving the gripper, pressure tests can be performed on different materials, etc.
    The scenarios are:
    a. Microscale elastic modulus test of hydrogel(eg. AFM probe);
    b. Performance test of biomimetic material in the mouth area of Nepenthes;
    c. Other related research
MM-500 Motorized Micromanipulator & Patch Clamp Experiment
MM-500 Motorized Micromanipulator & R480 Nanoliter Injection Pump
MM-500 Motorized Micromanipulator & KDS Legato 130 Microsyringe Pump

To learn more about micromanipulators, click here.

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