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69100 Rotational Digital Stereotaxic Instruments for Mice and Rat

The mouse head can be easily rotated flexibility so as to adjust the level of the skull. The accuracy of mediolateral rotation perfectly solves the bleeding problem when you inject through the venous sinus. Alignment Indicator can feedback whether the height of the animal’s head is horizontal. Centering Scope helps find Bregma and Lambda points. And you don’t need to set up Bregma repeatedly.

Technical Specifications

  • Features
  • Technical Specifications
  • Available Mode
  • References

1. Fitted with a sagittal positioning plate design, To minimize the levelness, inclination and alignment of the skull.

2. Apparatus improves experiment efficiency, and the fixation process in animals is not repeated.

3. More detailed five-dimensional space positioning can meet the needs of other sites.

4. The operation arm has been tested by the motor for 100,000 times, which makes it more durable.

5. With 40X magnifier and horizontal calibrator, the skull flattening speed is faster and the brain area positioning accuracy is higher.

6. Can be combined with inhalation anesthesia machine, animal mortality is low, the risk of surgery is small.

Item Description
Tri-axial displacement Range in Sagittal plate (X, Y, Z axis) 30mm
left and right rotation Angle adjustment range in Sagittal plate ±30°
Swing the Angle up and down to adjust the range in Sagittal plate ±10°
horizontal Angle adjustment range in Center floor ±10°
Displacement distance of operating arm (X, Y, Z axis) 80mm
Plate size 400mm X 325mm
The mirror is still served at magnification 40X
Horizontal calibrator reading resolution 0.01mm
  • Model Product Description
    69100 Rotational Digital Stereotaxic Instrument for Mouse, Single M.
    69101 Rotational Digital Stereotaxic Instrument for Mouse, Dual M.
    69102 Rotational Digital Stereotaxic Instrument for Rat, Single M.
    69103 Rotational Digital Stereotaxic Instrument for Rat, Dual M.
    69100S Stereotaxic Frame for Rat or Mouse, Single Rail
    69100D Stereotaxic Frame for Rat or Mouse, Dual Rail
    69130 Centering Scope 40X Accessories
    69131 Alignment Indicator
    69110 Mouse Anesthesia Adapter with Tubing(<30g)
    69111 Mouse Anesthesia Adapter with Tubing(30~70g)
    69112 Rat Anesthesia Adapter with Tubing
    69113 15°Angle Adaptor
    69114 60°Ear Bars for Mouse, One pair
    69115 18°Ear Bars for Rat, One pair
1. Yang Y, Cui Y, Sang K, Dong Y, Ni Z, Ma S, Hu H. Ketamine blocks bursting in the lateral habenula to rapidly relieve depression. Nature. 2018 Feb 14;554(7692):317-322.
2. Cui Y, Yang Y, Ni Z, Dong Y, Cai G, Foncelle A, Ma S, Sang K, Tang S, Li Y, Shen Y, Berry H, Wu S, Hu H. Astroglial Kir4.1 in the lateral habenula drives neuronal bursts in depression. Nature. 2018 Feb 14;554(7692):323-327.
3. Zhou H, Xiong GJ, Jing L, Song NN, Pu DL, Tang X, He XB, Xu FQ, Huang JF, Li LJ, Richter-Levin G, Mao RR, Zhou QX, Ding YQ, Xu L. The interhemispheric CA1 circuit governs rapid generalisation but not fear memory. Nat Commun. 2017 Dec 19;8(1):2190.
4. Huang L, Yuan T, Tan M, Xi Y, Hu Y, Tao Q, Zhao Z, Zheng J, Han Y, Xu F, Luo M, Sollars PJ, Pu M, Pickard GE, So KF, Ren C. A retinoraphe projection regulates serotonergic activity and looming-evoked defensive behaviour. Nat Commun. 2017 Mar 31;8:14908.
5. Liu Y, Lai S, Ma W, Ke W, Zhang C, Liu S, Zhang Y, Pei F, Li S, Yi M, Shu Y, Shang Y, Liang J, Huang Z. CDYL suppresses epileptogenesis in mice through repression of axonal Nav1.6 sodium channel expression. Nat Commun. 2017 Aug 25;8(1):355.
6. Wang GQ, Cen C, Li C, Cao S, Wang N, Zhou Z, Liu XM, Xu Y, Tian NX, Zhang Y, Wang J, Wang LP, Wang Y. Deactivation of excitatory neurons in the prelimbic cortex via Cdk5 promotes pain sensation and anxiety. Nat Commun. 2015 Jul 16;6:7660.
7. Li WG, Liu MG, Deng S, Liu YM, Shang L, Ding J, Hsu TT, Jiang Q, Li Y, Li F, Zhu MX, Xu TL. ASIC1a regulates insular long-term depression and is required for the extinction of conditioned taste aversion. Nat Commun. 2016 Dec 7;7:13770.
8. Hao X, Gu H, Chen C, Huang D, Zhao Y, Xie L, Zou Y, Shu HS, Zhang Y, He X, Lai X, Zhang X, Zhou BO, Zhang CC, Chen GQ, Yu Z, Yang Y, Zheng J. Metabolic Imaging Reveals a Unique Preference of Symmetric Cell Division and Homing of Leukemia-Initiating Cells in an Endosteal Niche. Cell Metab. 2019 Apr 2;29(4):950-965.
9. Diao Y, Cui L, Chen Y, Burbridge TJ, Han W, Wirth B, Sestan N, Crair MC, Zhang J. Reciprocal Connections Between Cortex and Thalamus Contribute to Retinal Axon Targeting to Dorsal Lateral Geniculate Nucleus. Cereb Cortex. 2018 Apr 1;28(4):1168-1182.
10. Chen X, Guo Y, Feng J, Liao Z, Li X, Wang H, Li X, He J. Encoding and retrieval of artificial visuoauditory memory traces in the auditory cortex requires the entorhinal cortex. J Neurosci. 2013 Jun 12;33(24):9963-74.

Articles

                                                 Stereotaxic Anesthesia Solutions

This program aims to be specially used for neuroscience research in rodent’s animals. Such as

  • development of animal neurological diseases models(Alzheimer’s and Parkinson’s diseases, cerebral and spinal cord injury etc.), drug injection to brain,
  • cannula implantation for long-term drug administration, nervous stimulation,
  • physiological signal record, microdialysis
  • probe implantation and so on
  • Configure information:

    Part No. Configurations Mouse Rat
    R500IE Compact Small Animal Anesthesia Machine/Easy Fill-4L
    R510-29/30 Air Pump (HF) 220V/110V
    V100 Induction Chamber-Mouse (15cm*10cm*10cm)
    V101 Induction Chamber-Rat (24cm*12cm*18cm)
    69100 Rotational Digital Stereotaxic Instrument for Mouse, Single M.
    69102 Rotational Digital Stereotaxic Instrument for Rat, Single M.
    69100 Rotational Digital Stereotaxic Instrument for Mouse, Single M.
    R510-31-6 Gas Filter Canister, Large, pkg of 6pcs
    R546Pro Gas Evacuation Apparatus with Weight Monitoring, 110-240V

     

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