RFLSI Ⅲ Laser Speckle Contrast Imaging System
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RFLSI Ⅲ Laser Speckle Contrast Imaging System
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RFLSI Ⅲ Laser Speckle Contrast Imaging System

A robust blood perfusion imager system, with advanced software, allows you to real-time blood flow monitoring and recording. Also, visualize and quantify data quickly, shorten the experiment time, obtain results easily.

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Overview

RFLSI is based on the LSCI (Laser Speckle Contrast Imaging) technology design. With the advantages of its non-contact, high frame-rate, high spatial resolution, it can be used to full-field real-time monitor and record blood flow of rodents and any exposed tissues or organs for microcirculation imaging.

This system is designed for pre-clinical research in areas like ischemic stroke, lower limbs, mesentery, etc. Multi-Output includes blood flow images and videos (4.2 million pixels), quantified data, diameter analysis.

Applications:

  • Cerebral blood perfusion monitoring
  • MCAO model assessment
  • Cortical spreading depression observation
  • Hind-limb ischemia research
  • Skin burn/skin flap transplantation
  • Organ microcirculation observation
  • Noninvasive microvascular assessment

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Advantages

Reliable Data Measurement

Stable laser output for reliable and consistent measurement over minutes, hours and days, accuracy up to 0.1 PU, easy to control variables.

Full-Frame HD Image & Video

High-definition camera (full-frame 2048x2048 resolution) helps you see the blood vessel endings and opens the world of microcirculation imaging.

High Frame Rate

A high-speed camera (up to 120 FPS) allows you to record rapid changes every second and record more details of blood vessel changes after intervention.

Quantified Visualization Data

Full-field monitoring, quantitative analysis. Multi-output includes vascular perfusion volume, vessel diameter, vessel angle, etc., also offline state analysis available.

Guaranteed to Run Smoothly

2*USB 3.0 compatible, data acquisition, rapidly transformed blood flow imaging and video that does not freeze, and decrease delay.

Easy Operation

Unique non-contact, no need for a special darkroom environment. Autofocus function, easy to use, get image data and video in seconds.

Successful Cases

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Journal: Nature Communication

Use the laser speckle to observe changes in cerebral blood flow after lymphatic ablation, and quantitative analysis. Explore whether meningeal lymphatics are involved in clearing extravasated erythrocytes in CSF after SAH.

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Journal: EBioMedicine

Use LSCI to real-time detect regional velocity and distribution of blood flow and perfused blood vessel of sciatic nerve and foot pads, and also analyze image to better evaluate the therapeutic effect of small molecule substances on diabetes.

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Journal: Shock

It was proved for the first time that 14-3-3 -3ζ-c-src-integrin-β3 complex was formed during platelet activation. A new strategy was offered for the development of safe and effective antithrombotic therapy.

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Ready to Get Started?

We have done RFLSI online demo with more than 200 global customers and got exemplary feedback from them. Welcome to try our free virtual demo to learn how our RFLSI can help in advanced scientific research.

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Clients Say

Clinical & Experimental Epilepsy

“I couldn’t suggest further hardware features as I feel everything the user would need is there. The quality of the images is wonderful.....”

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--Samuel M. Flaherty

The University of Manchester

Stroke & Vascular Function

“We can use the Laser Speckle Imaging System to observe the 5th branch of Mesentery.”

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--Yi-Je (Jay) Chen, Ph. D.

丨Assistant Professor, UC Davis

Brain Injury

“The instrument and the software worked really well and are pretty straightforward to use so the general feedback is highly positive."

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Istituto di ricerche farmacologiche Mario Negri

Our Customer

If you are a researcher in neuroscience, dermatology or ophthalmology and looking for clear contrasts, RFLSI Ⅲ can help you get the results you need.

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